HZSM-5 was loaded on the cordierite monolithic, and the effect of porous size of the carrier, solid content in slurry, solvent and binder on the loaded amount and loaded quality has been studied. The results show that the big channel, high solid content and the addition of ethanol solvent could increase the loaded amount of the active components in each immobilization process, yet the loaded quality of HZSM5/monolithic catalyst was decreased. While silica sol could significantly increas ethe loaded quality of HZSM5 on monolithic. In conversion of methanol to gasoline, HZSM-5/ monolithic catalyst exhibited high methanol conversion, and oil yield could reach 30.53% at 380 ℃.